Most of the mass of the universe consists of dark matter. And we can recognize its existence only indirectly: we see its gravitational effects, the acceleration of other known constituents of the universe. In the same way, we know of the existence of ME/CFS mainly form its effects: huge damages in the lives of patients affected.
Physicists are now trying to identify the exact nature of dark matter and they are excited by this new field. Unfortunately, physicians don’t always share the same excitement when it comes to investigating the “dark matter of medicine”.